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Predicting population coverage of T-cell epitope-based diagnostics and vaccines

BACKGROUND: T cells recognize a complex between a specific major histocompatibility complex (MHC) molecule and a particular pathogen-derived epitope. A given epitope will elicit a response only in individuals that express an MHC molecule capable of binding that particular epitope. MHC molecules are...

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Main Authors: Bui, Huynh-Hoa, Sidney, John, Dinh, Kenny, Southwood, Scott, Newman, Mark J, Sette, Alessandro
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2006
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1513259/
https://ncbi.nlm.nih.gov/pubmed/16545123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-7-153
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