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Development of an epitope conservancy analysis tool to facilitate the design of epitope-based diagnostics and vaccines

BACKGROUND: In an epitope-based vaccine setting, the use of conserved epitopes would be expected to provide broader protection across multiple strains, or even species, than epitopes derived from highly variable genome regions. Conversely, in a diagnostic and disease monitoring setting, epitopes tha...

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Detalhes bibliográficos
Main Authors: Bui, Huynh-Hoa, Sidney, John, Li, Wei, Fusseder, Nicolas, Sette, Alessandro
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2233646/
https://ncbi.nlm.nih.gov/pubmed/17897458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-8-361
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