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Development of an epitope conservancy analysis tool to facilitate the design of epitope-based diagnostics and vaccines

BACKGROUND: In an epitope-based vaccine setting, the use of conserved epitopes would be expected to provide broader protection across multiple strains, or even species, than epitopes derived from highly variable genome regions. Conversely, in a diagnostic and disease monitoring setting, epitopes tha...

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Autori principali: Bui, Huynh-Hoa, Sidney, John, Li, Wei, Fusseder, Nicolas, Sette, Alessandro
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2233646/
https://ncbi.nlm.nih.gov/pubmed/17897458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-8-361
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