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TNF-α mediates chemokine and cytokine expression and renal injury in cisplatin nephrotoxicity

The purpose of these studies was to examine the role of cytokines in the pathogenesis of cisplatin nephrotoxicity. Injection of mice with cisplatin (20 mg/kg) led to severe renal failure. The expression of cytokines, chemokines, and ICAM-1 in kidney was measured by ribonuclease protection assays and...

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Hlavní autoři: Ramesh, Ganesan, Reeves, W. Brian
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2002
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC151130/
https://ncbi.nlm.nih.gov/pubmed/12235115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI15606
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