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TNF-α mediates increased susceptibility to ischemic AKI in diabetes

Diabetes is a risk factor for the development of acute kidney injury (AKI) in humans and rodents. However, the mechanistic basis for this observation is unknown. The present studies evaluated the role of inflammation and TNF-α in ischemic AKI in a model of type 2 diabetes mellitus (DM). Diabetic (db...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Gao, Guofeng, Zhang, Binzhi, Ramesh, Ganesan, Betterly, Daniel, Tadagavadi, Raghu K., Wang, Weiwei, Reeves, W. Brian
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3602710/
https://ncbi.nlm.nih.gov/pubmed/23283990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00533.2012
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