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TNF-α mediates increased susceptibility to ischemic AKI in diabetes

Diabetes is a risk factor for the development of acute kidney injury (AKI) in humans and rodents. However, the mechanistic basis for this observation is unknown. The present studies evaluated the role of inflammation and TNF-α in ischemic AKI in a model of type 2 diabetes mellitus (DM). Diabetic (db...

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Detalhes bibliográficos
Main Authors: Gao, Guofeng, Zhang, Binzhi, Ramesh, Ganesan, Betterly, Daniel, Tadagavadi, Raghu K., Wang, Weiwei, Reeves, W. Brian
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3602710/
https://ncbi.nlm.nih.gov/pubmed/23283990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00533.2012
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