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TLR4 Signaling Mediates Inflammation and Tissue Injury in Nephrotoxicity

The molecular mechanisms of acute kidney injury (AKI) remain unclear. Toll-like receptors (TLRs), widely expressed on leukocytes and kidney epithelial cells, regulate innate and adaptive immune responses. The present study examined the role of TLR signaling in cisplatin-induced AKI. Cisplatin-treate...

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Bibliografische gegevens
Hoofdauteurs: Zhang, Binzhi, Ramesh, Ganesan, Uematsu, Satoshi, Akira, Shizuo, Reeves, W. Brian
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society of Nephrology 2008
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2386719/
https://ncbi.nlm.nih.gov/pubmed/18256356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2007090982
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