Genetic evidence that HNF-1α–dependent transcriptional control of HNF-4α is essential for human pancreatic β cell function

Mutations in the genes encoding hepatocyte nuclear factor 4α (HNF-4α) and HNF-1α impair insulin secretion and cause maturity onset diabetes of the young (MODY). HNF-4α is known to be an essential positive regulator of HNF-1α. More recent data demonstrates that HNF-4α expression is dependent on HNF-1...

詳細記述

書誌詳細

出版年:	J Clin Invest
主要な著者:	Hansen, Sara K., Párrizas, Marcelina, Jensen, Maria L., Pruhova, Stepanka, Ek, Jakob, Boj, Sylvia F., Johansen, Anders, Maestro, Miguel A., Rivera, Francisca, Eiberg, Hans, Andel, Michal, Lebl, Jan, Pedersen, Oluf, Ferrer, Jorge, Hansen, Torben
フォーマット:	Artigo
言語:	Inglês
出版事項:	American Society for Clinical Investigation 2002
主題:	Article
オンライン･アクセス:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC151122/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12235114/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI15085
タグ:	タグ追加 タグなし, このレコードへの初めてのタグを付けませんか!