Chargement en cours...
p53 induction and activation of DDR1 kinase counteract p53-mediated apoptosis and influence p53 regulation through a positive feedback loop
DDR1, discoidin domain receptor 1, belongs to a subfamily of tyrosine kinase receptors with an extracellular domain homologous to Dictyostellium discoideum protein discoidin 1. We showed that DDR1 is a direct p53 transcriptional target, and that DNA damage induced a p53-dependent DDR1 response assoc...
Enregistré dans:
| Auteurs principaux: | , , , , , , |
|---|---|
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2003
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC151063/ https://ncbi.nlm.nih.gov/pubmed/12628922 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg129 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|