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Blockade of TGF-β inhibits mammary tumor cell viability, migration, and metastases
TGF-βs are potent inhibitors of epithelial cell proliferation. However, in established carcinomas, autocrine/paracrine TGF-β interactions can enhance tumor cell viability and progression. Thus, we studied the effect of a soluble Fc:TGF-β type II receptor fusion protein (Fc:TβRII) on transgenic and t...
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| Main Authors: | , , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Clinical Investigation
2002
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC151012/ https://ncbi.nlm.nih.gov/pubmed/12070302 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI15234 |
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