Leptin reverses insulin resistance and hepatic steatosis in patients with severe lipodystrophy

Lipodystrophy is a rare disorder that is characterized by selective loss of subcutaneous and visceral fat and is associated with hypertriglyceridemia, hepatomegaly, and disordered glucose metabolism. It has recently been shown that chronic leptin treatment ameliorates these abnormalities. Here we sh...

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Главные авторы: Petersen, Kitt Falk, Oral, Elif Arioglu, Dufour, Sylvie, Befroy, Douglas, Ariyan, Charlotte, Yu, Chunli, Cline, Gary W., DePaoli, Alex M., Taylor, Simeon I., Gorden, Phillip, Shulman, Gerald I.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Clinical Investigation 2002
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC150981/
https://ncbi.nlm.nih.gov/pubmed/12021250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI15001
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