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Leptin reverses insulin resistance and hepatic steatosis in patients with severe lipodystrophy

Lipodystrophy is a rare disorder that is characterized by selective loss of subcutaneous and visceral fat and is associated with hypertriglyceridemia, hepatomegaly, and disordered glucose metabolism. It has recently been shown that chronic leptin treatment ameliorates these abnormalities. Here we sh...

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Détails bibliographiques
Auteurs principaux: Petersen, Kitt Falk, Oral, Elif Arioglu, Dufour, Sylvie, Befroy, Douglas, Ariyan, Charlotte, Yu, Chunli, Cline, Gary W., DePaoli, Alex M., Taylor, Simeon I., Gorden, Phillip, Shulman, Gerald I.
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 2002
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC150981/
https://ncbi.nlm.nih.gov/pubmed/12021250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI15001
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