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Skeletal Muscle Insulin Resistance Promotes Increased Hepatic De Novo Lipogenesis, Hyperlipidemia, and Hepatic Steatosis in the Elderly

Aging is closely associated with muscle insulin resistance, hyperlipidemia, nonalcoholic fatty liver disease (NAFLD), and type 2 diabetes. We examined the hypothesis that muscle insulin resistance in healthy aging promotes increased hepatic de novo lipogenesis (DNL) and hyperlipidemia by altering th...

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書誌詳細
主要な著者: Flannery, Clare, Dufour, Sylvie, Rabøl, Rasmus, Shulman, Gerald I., Petersen, Kitt Falk
フォーマット: Artigo
言語:Inglês
出版事項: American Diabetes Association 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3478531/
https://ncbi.nlm.nih.gov/pubmed/22829450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db12-0206
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