Promotion of osteoclast survival and antagonism of bisphosphonate-induced osteoclast apoptosis by glucocorticoids

Glucocorticoids depress bone formation by inhibiting osteoblastogenesis and increasing osteoblast apoptosis. However, the role of bone resorption in the initial rapid phase of bone loss characteristic of glucocorticoid-induced osteoporosis is unexplained, and the reason for the efficacy of bisphosph...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Weinstein, Robert S., Chen, Jin-Ran, Powers, Cara C., Stewart, Scott A., Landes, Reid D., Bellido, Teresita, Jilka, Robert L., Parfitt, A. Michael, Manolagas, Stavros C.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 2002
Assuntos:	Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC150947/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11956241/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI14538
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