Promotion of osteoclast survival and antagonism of bisphosphonate-induced osteoclast apoptosis by glucocorticoids

Glucocorticoids depress bone formation by inhibiting osteoblastogenesis and increasing osteoblast apoptosis. However, the role of bone resorption in the initial rapid phase of bone loss characteristic of glucocorticoid-induced osteoporosis is unexplained, and the reason for the efficacy of bisphosph...

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Опубликовано в::	J Clin Invest
Главные авторы:	Weinstein, Robert S., Chen, Jin-Ran, Powers, Cara C., Stewart, Scott A., Landes, Reid D., Bellido, Teresita, Jilka, Robert L., Parfitt, A. Michael, Manolagas, Stavros C.
Формат:	Artigo
Язык:	Inglês
Опубликовано:	American Society for Clinical Investigation 2002
Предметы:	Article
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC150947/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11956241/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI14538
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