Promotion of osteoclast survival and antagonism of bisphosphonate-induced osteoclast apoptosis by glucocorticoids

Glucocorticoids depress bone formation by inhibiting osteoblastogenesis and increasing osteoblast apoptosis. However, the role of bone resorption in the initial rapid phase of bone loss characteristic of glucocorticoid-induced osteoporosis is unexplained, and the reason for the efficacy of bisphosph...

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Publikašuvnnas:	J Clin Invest
Váldodahkkit:	Weinstein, Robert S., Chen, Jin-Ran, Powers, Cara C., Stewart, Scott A., Landes, Reid D., Bellido, Teresita, Jilka, Robert L., Parfitt, A. Michael, Manolagas, Stavros C.
Materiálatiipa:	Artigo
Giella:	Inglês
Almmustuhtton:	American Society for Clinical Investigation 2002
Fáttát:	Article
Liŋkkat:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC150947/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11956241/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI14538
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