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Presented antigen from damaged pancreatic β cells activates autoreactive T cells in virus-mediated autoimmune diabetes

The induction of autoimmunity by viruses has been attributed to numerous mechanisms. In mice, coxsackievirus B4 (CB4) induces insulin-dependent diabetes mellitus (IDDM) resembling the final step of disease progression in humans. The immune response following the viral insult clearly precipitates IDD...

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Hlavní autoři: Horwitz, Marc S., Ilic, Alex, Fine, Cody, Rodriguez, Enrique, Sarvetnick, Nora
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2002
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC150813/
https://ncbi.nlm.nih.gov/pubmed/11781353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI11198
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