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B7-1 mediated costimulation regulates pancreatic autoimmunity
Costimulation by B7-1 and B7-2 molecules results in divergent biological effects. This is particularly striking in the NOD mouse, since the lack of B7-2 leads to complete protection from autoimmunity, whereas the B7-1 deficiency causes exacerbation of disease. We tested the hypothesis that B7-1 cost...
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| Publicado en: | Mol Immunol |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2007
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4275027/ https://ncbi.nlm.nih.gov/pubmed/17289146 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2006.12.008 |
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