Cooperative B7-1/2 (CD80/CD86) and B7-DC Costimulation of CD4(+) T Cells Independent of the PD-1 Receptor

B7-DC is a recently discovered member of the B7 family that binds to PD-1 and is selectively expressed by dendritic cells (DCs). It has been shown to either costimulate or inhibit T cell responses. To assess the role of B7-DC in DC–T cell interactions, DCs from B7-DC knockout (KO) mice were generate...

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Detalhes bibliográficos
Main Authors: Shin, Tahiro, Kennedy, Gene, Gorski, Kevin, Tsuchiya, Haruo, Koseki, Haruhiko, Azuma, Miyuki, Yagita, Hideo, Chen, Lieping, Powell, Jonathan, Pardoll, Drew, Housseau, Franck
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2003
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2196092/
https://ncbi.nlm.nih.gov/pubmed/12847135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20030242
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