Aspirin Induces Apoptosis through Release of Cytochrome c from Mitochondria

Nonsteroidal anti-inflammatory drugs (NSAID) reduce the risk for cancer, due to their antiproliferative and apoptosis-inducing effects. A critical pathway for apoptosis involves the release of cytochrome c from mitochondria, which then interacts with Apaf-1 to activate caspase proteases that orchest...

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Главные авторы: Zimmermann, Katja C, Waterhouse, Nigel J, Goldstein, Joshua C, Schuler, Martin, Green, Douglas R
Формат: Artigo
Язык:Inglês
Опубликовано: Nature America, Inc. 2000
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1508093/
https://ncbi.nlm.nih.gov/pubmed/11228543
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