Polyamines directly induce release of cytochrome c from heart mitochondria.

Cytochrome c release from mitochondria to the cytosol represents a critical step in apoptosis, correlated to the activation of the caspase cascade. In this report, we show that addition of micromolar concentrations of polyamines to isolated rat heart mitochondria induces the release of cytochrome c....

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Bibliografiske detaljer
Main Authors: Stefanelli, C, Stanic', I, Zini, M, Bonavita, F, Flamigni, F, Zambonin, L, Landi, L, Pignatti, C, Guarnieri, C, Caldarera, C M
Format: Artigo
Sprog:Inglês
Udgivet: 2000
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1221027/
https://ncbi.nlm.nih.gov/pubmed/10769194
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