Polyamines directly induce release of cytochrome c from heart mitochondria.

Cytochrome c release from mitochondria to the cytosol represents a critical step in apoptosis, correlated to the activation of the caspase cascade. In this report, we show that addition of micromolar concentrations of polyamines to isolated rat heart mitochondria induces the release of cytochrome c....

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Autors principals: Stefanelli, C, Stanic', I, Zini, M, Bonavita, F, Flamigni, F, Zambonin, L, Landi, L, Pignatti, C, Guarnieri, C, Caldarera, C M
Format: Artigo
Idioma:Inglês
Publicat: 2000
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1221027/
https://ncbi.nlm.nih.gov/pubmed/10769194
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