Polyamines directly induce release of cytochrome c from heart mitochondria.

Cytochrome c release from mitochondria to the cytosol represents a critical step in apoptosis, correlated to the activation of the caspase cascade. In this report, we show that addition of micromolar concentrations of polyamines to isolated rat heart mitochondria induces the release of cytochrome c....

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Detalles Bibliográficos
Main Authors: Stefanelli, C, Stanic', I, Zini, M, Bonavita, F, Flamigni, F, Zambonin, L, Landi, L, Pignatti, C, Guarnieri, C, Caldarera, C M
Formato: Artigo
Idioma:Inglês
Publicado: 2000
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1221027/
https://ncbi.nlm.nih.gov/pubmed/10769194
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