Gads/Grb2-Mediated Association with LAT Is Critical for the Inhibitory Function of Gab2 in T Cells

A docking protein, Gab2, is recruited to the vicinity of the TCR complex and inhibits downstream signaling by interaction with negative regulators. However, the molecular mechanisms of this recruitment remain unclear. We have found that Gab2 associates with LAT upon TCR stimulation and that LAT is e...

Szczegółowa specyfikacja

Opis bibliograficzny

Wydane w:	Mol Cell Biol
Główni autorzy:	Yamasaki, Sho, Nishida, Keigo, Sakuma, Machie, Berry, Donna, McGlade, C. Jane, Hirano, Toshio, Saito, Takashi
Format:	Artigo
Język:	Inglês
Wydane:	Taylor & Francis 2003
Hasła przedmiotowe:	Cell Growth and Development
Dostęp online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC150736/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12640133/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.7.2515-2529.2003
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