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Understanding the Mechanism of Recognition of Gab2 by the N-SH2 Domain of SHP2

Gab2 is a scaffold protein with a crucial role in colocalizing signaling proteins and it is involved in the regulation of several important molecular pathways. SHP2 is a protein phosphatase that binds, through its two SH2 domains, specific consensus sequences presenting a phosphorylated tyrosine loc...

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Hlavní autoři: Lorenzo Visconti, Francesca Malagrinò, Livia Pagano, Angelo Toto
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI AG 2020-06-01
Edice:Life
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On-line přístup:https://www.mdpi.com/2075-1729/10/6/85
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