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Jun N-Terminal Kinase 1 Mediates Transcriptional Induction of Matrix Metalloproteinase 9 Expression

Tumor cell invasion and metastasis require precise coordination of adherence to extracellular matrix (ECM) and controlled degradation of its components. Invasive cells secrete proteolytic enzymes known as matrix metalloproteinases (MMPs) which degrade specific basement membrane molecules. Expression...

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Main Authors: Crowe, David L, Tsang, Kenneth J, Shemirani, Babak
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2001
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1505027/
https://ncbi.nlm.nih.gov/pubmed/11326313
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