Jun N-Terminal Kinase 1 Mediates Transcriptional Induction of Matrix Metalloproteinase 9 Expression

Tumor cell invasion and metastasis require precise coordination of adherence to extracellular matrix (ECM) and controlled degradation of its components. Invasive cells secrete proteolytic enzymes known as matrix metalloproteinases (MMPs) which degrade specific basement membrane molecules. Expression...

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Bibliographische Detailangaben
Hauptverfasser: Crowe, David L, Tsang, Kenneth J, Shemirani, Babak
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2001
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1505027/
https://ncbi.nlm.nih.gov/pubmed/11326313
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