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Reactive Oxygen Species Control Senescence-Associated Matrix Metalloproteinase-1 through c-Jun-N-Terminal Kinase

The lifetime exposure of organisms to oxidative stress influences many aging processes which involve the turnover of the extracellular matrix. In this study, we identify the redox-responsive molecular signals that drive senescence-associated (SA) matrix metalloproteinase-1 (MMP-1) expression. Precis...

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Detalhes bibliográficos
Main Authors: Dasgupta, Jaya, Kar, Supriya, Liu, Rong, Joseph, Joy, Kalayanaram, Balaraman, Remington, S. James, Chen, Cheshi, Melendez, J. Andres
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2913426/
https://ncbi.nlm.nih.gov/pubmed/20648623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.22193
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