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Redox-control of Matrix Metalloproteinase-1: A critical link between free radicals, matrix remodeling and degenerative disease.

Many degenerative disease processes associated with aging result from enhanced extracellular matrix (ECM) breakdown. Concomitant with aberrant matrix destruction are alterations in levels of reactive oxygen species (ROS) generating and detoxification systems. ROS function as second messengers due to...

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Bibliographische Detailangaben
Hauptverfasser: Kar, Supriya, Subbaram, Sita, Carrico, Pauline M., Melendez, J. Andrés
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2991541/
https://ncbi.nlm.nih.gov/pubmed/20804863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.resp.2010.08.019
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