Spatiotemporal induction of matrix metalloproteinase-9 transcription after discrete myocardial injury

Radiofrequency (RF) ablation of the myocardium causes discrete sites of injury. RF scars can expand, altering the extracellular matrix (ECM) structure and the continuity of the electrical syncytium of the adjacent myocardium. Matrix metalloproteinases (MMPs), such as MMP-9, contribute to ECM remodel...

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Главные авторы: Mukherjee, Rupak, Colbath, Gregory P., Justus, Charles D., Bruce, James A., Allen, Claire M., Hewett, Kenneth W., Saul, J. Philip, Gourdie, Robert G., Spinale, Francis G.
Формат: Artigo
Язык:Inglês
Опубликовано: Federation of American Societies for Experimental Biology 2010
Предметы:
Research Communications
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2996910/
https://ncbi.nlm.nih.gov/pubmed/20530752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.10-155531
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