Spatiotemporal induction of matrix metalloproteinase-9 transcription after discrete myocardial injury

Radiofrequency (RF) ablation of the myocardium causes discrete sites of injury. RF scars can expand, altering the extracellular matrix (ECM) structure and the continuity of the electrical syncytium of the adjacent myocardium. Matrix metalloproteinases (MMPs), such as MMP-9, contribute to ECM remodel...

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Main Authors: Mukherjee, Rupak, Colbath, Gregory P., Justus, Charles D., Bruce, James A., Allen, Claire M., Hewett, Kenneth W., Saul, J. Philip, Gourdie, Robert G., Spinale, Francis G.
Format: Artigo
Sprog:Inglês
Udgivet: Federation of American Societies for Experimental Biology 2010
Fag:
Research Communications
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2996910/
https://ncbi.nlm.nih.gov/pubmed/20530752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.10-155531
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