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Differential Effect of Wall Tension on Matrix Metalloproteinase Promoter Activation in the Thoracic Aorta
BACKGROUND: Vascular remodeling relies upon extracellular matrix restructuring by the matrix metalloproteinases (MMPs). Induction of MMP-2 and MMP-9 by biological signaling molecules has been defined, but whether a mechanical stimulus such as elevated wall tension may generate MMP promoter activatio...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2859117/ https://ncbi.nlm.nih.gov/pubmed/19375723 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jss.2008.12.033 |
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