Cisplatinum and Taxol Induce Different Patterns of p53 Phosphorylation

Posttranslational modifications of p53 induced by two widely used anticancer agents, cisplatinum (DDP) and taxol were investigated in two human cancer cell lines. Although both drugs were able to induce phosphorylation at serine 20 (Ser20), only DDP treatment induced p53 phosphorylation at serine 15...

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Hauptverfasser: Damia, Giovanna, Filiberti, Laura, Vikhanskaya, Faina, Carrassa, Laura, Taya, Yoichi, D'incalci, Maurizio, Broggini, Massimo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2001
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1505020/
https://ncbi.nlm.nih.gov/pubmed/11326311
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