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Introduction of wild-type p53 in a human ovarian cancer cell line not expressing endogenous p53.

Utilizing a temperature sensitive p53 mutant (pLTRp53cGval135) which expresses mutant p53 at 37 degrees C and a wild-type like p53 at 32 degrees C, we transfected a human ovarian cancer cell line (SKOV3) which does not express endogenous p53. Among the different clones obtained, we selected three cl...

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Bibliografiske detaljer
Main Authors: Vikhanskaya, F, Erba, E, D'Incalci, M, Broggini, M
Format: Artigo
Sprog:Inglês
Udgivet: 1994
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC307923/
https://ncbi.nlm.nih.gov/pubmed/8152906
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