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Defining Characteristics of Types I and II Apoptotic Cells in Response to TRAIL

Type I cells have been defined to be independent of mitochondria for the induction of Fas death receptor-mediated apoptosis, whereas Type II cells are mitochondria-dependent. Knock-out studies in mice show that thymocytes are Type I and liver cells are Type II. We have previously shown that primary...

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Bibliographic Details
Main Authors: Özören, Nesrin, El-Deiry, Wafik S
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2002
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1503670/
https://ncbi.nlm.nih.gov/pubmed/12407450
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