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Detection of Spontaneous Schwannomas by MRI in a Transgenic Murine Model of Neurofibromatosis Type 2

Spontaneous schwannomas were detected by magnetic resonance imaging (MRI) in a transgenic murine model of neurofibromatosis type 2 (NF2) expressing a dominant mutant form of merlin under the Schwann cell-specific P0 promoter. Approximately 85% of the investigated mice showed putative tumors by 24 mo...

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Bibliografiske detaljer
Main Authors: Messerli, SM, Tang, Y, Giovannini, M, Bronsonx, R, Weissleder, R, Breakefield, XO
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2002
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1503664/
https://ncbi.nlm.nih.gov/pubmed/12407444
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