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Imaging and therapy of experimental schwannomas using HSV amplicon vector-encoding apoptotic protein under Schwann cell promoter

Schwannomas are benign tumors forming along peripheral nerves that can cause deafness, pain and paralysis. Current treatment involves surgical resection, which can damage associated nerves. To achieve tumor regression without damage to nerve fibers, we generated an HSV amplicon vector in which the a...

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Detalhes bibliográficos
Main Authors: Prabhakar, S, Brenner, GJ, Sung, B, Messerli, SM, Mao, J, Sena-Esteves, M, Stemmer-Rachamimov, A, Tannous, B, Breakefield, XO
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2857743/
https://ncbi.nlm.nih.gov/pubmed/19834516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cgt.2009.71
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