Imaging and therapy of experimental schwannomas using HSV amplicon vector-encoding apoptotic protein under Schwann cell promoter

Schwannomas are benign tumors forming along peripheral nerves that can cause deafness, pain and paralysis. Current treatment involves surgical resection, which can damage associated nerves. To achieve tumor regression without damage to nerve fibers, we generated an HSV amplicon vector in which the a...

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Main Authors: Prabhakar, S, Brenner, GJ, Sung, B, Messerli, SM, Mao, J, Sena-Esteves, M, Stemmer-Rachamimov, A, Tannous, B, Breakefield, XO
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2009
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2857743/
https://ncbi.nlm.nih.gov/pubmed/19834516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cgt.2009.71
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