Imaging and therapy of experimental schwannomas using HSV amplicon vector-encoding apoptotic protein under Schwann cell promoter

Schwannomas are benign tumors forming along peripheral nerves that can cause deafness, pain and paralysis. Current treatment involves surgical resection, which can damage associated nerves. To achieve tumor regression without damage to nerve fibers, we generated an HSV amplicon vector in which the a...

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Autors principals: Prabhakar, S, Brenner, GJ, Sung, B, Messerli, SM, Mao, J, Sena-Esteves, M, Stemmer-Rachamimov, A, Tannous, B, Breakefield, XO
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2857743/
https://ncbi.nlm.nih.gov/pubmed/19834516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cgt.2009.71
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