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Phosphoproteomic analysis of Her2/neu signaling and inhibition

Her2/neu (Her2) is a tyrosine kinase belonging to the EGF receptor (EGFR)/ErbB family and is overexpressed in 20–30% of human breast cancers. We sought to characterize Her2 signal transduction pathways further by using MS-based quantitative proteomics. Stably transfected cell lines overexpressing He...

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Detalhes bibliográficos
Main Authors: Bose, Ron, Molina, Henrik, Patterson, A. Scott, Bitok, John K., Periaswamy, Balamurugan, Bader, Joel S., Pandey, Akhilesh, Cole, Philip A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1502529/
https://ncbi.nlm.nih.gov/pubmed/16785428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0603948103
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