c-Myc Enhances Sonic Hedgehog-Induced Medulloblastoma Formation from Nestin-Expressing Neural Progenitors in Mice

Medulloblastomas are malignant brain tumors that arise in the cerebella of children. The presumed cells-of-origin are undifferentiated precursors of granule neurons that occupy the external granule layer (EGL) of the developing cerebellum. The overexpression of proteins that normally stimulate proli...

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Hauptverfasser: Rao, Ganesh, Pedone, Carolyn A, Coffin, Cheryl M, Holland, Eric C, Fults, Daniel W
Format: Artigo
Sprache:Inglês
Veröffentlicht: Neoplasia Press Inc. 2003
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1502413/
https://ncbi.nlm.nih.gov/pubmed/12869303
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