Aberrant Wnt/β-catenin signaling can induce chromosomal instability in colon cancer

Chromosomal instability (CIN), a hallmark of most colon tumors, may promote tumor progression by increasing the rate of genetic aberrations. CIN is thought to arise as a consequence of improper mitosis and spindle checkpoint activity, but its molecular basis remains largely elusive. The majority of...

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Detaylı Bibliyografya
Asıl Yazarlar: Hadjihannas, Michel V., Brückner, Martina, Jerchow, Boris, Birchmeier, Walter, Dietmaier, Wolfgang, Behrens, Jürgen
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2006
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1502302/
https://ncbi.nlm.nih.gov/pubmed/16815967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0604206103
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