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Aberrant Wnt/β-catenin signaling can induce chromosomal instability in colon cancer
Chromosomal instability (CIN), a hallmark of most colon tumors, may promote tumor progression by increasing the rate of genetic aberrations. CIN is thought to arise as a consequence of improper mitosis and spindle checkpoint activity, but its molecular basis remains largely elusive. The majority of...
में बचाया:
| मुख्य लेखकों: | , , , , , |
|---|---|
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
National Academy of Sciences
2006
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1502302/ https://ncbi.nlm.nih.gov/pubmed/16815967 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0604206103 |
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