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Computational prediction of methylation status in human genomic sequences

Epigenetic effects in mammals depend largely on heritable genomic methylation patterns. We describe a computational pattern recognition method that is used to predict the methylation landscape of human brain DNA. This method can be applied both to CpG islands and to non-CpG island regions. It comput...

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Hlavní autoři: Das, Rajdeep, Dimitrova, Nevenka, Xuan, Zhenyu, Rollins, Robert A., Haghighi, Fatemah, Edwards, John R., Ju, Jingyue, Bestor, Timothy H., Zhang, Michael Q.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2006
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1502297/
https://ncbi.nlm.nih.gov/pubmed/16818882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0602949103
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