gp130 signaling in proopiomelanocortin neurons mediates the acute anorectic response to centrally applied ciliary neurotrophic factor

Ciliary neurotrophic factor (CNTF) exerts anorectic effects by overcoming leptin resistance via activation of hypothalamic neurons. However, the exact site of CNTF action in the hypothalamus has not yet been identified. Using Cre-loxP-mediated recombination in vivo, we have selectively ablated the c...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Janoschek, Ruth, Plum, Leona, Koch, Linda, Münzberg, Heike, Diano, Sabrina, Shanabrough, Marya, Müller, Werner, Horvath, Tamas L., Brüning, Jens C.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2006
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1502296/
https://ncbi.nlm.nih.gov/pubmed/16818888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0600425103
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