gp130 signaling in proopiomelanocortin neurons mediates the acute anorectic response to centrally applied ciliary neurotrophic factor

Ciliary neurotrophic factor (CNTF) exerts anorectic effects by overcoming leptin resistance via activation of hypothalamic neurons. However, the exact site of CNTF action in the hypothalamus has not yet been identified. Using Cre-loxP-mediated recombination in vivo, we have selectively ablated the c...

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Detalhes bibliográficos
Main Authors: Janoschek, Ruth, Plum, Leona, Koch, Linda, Münzberg, Heike, Diano, Sabrina, Shanabrough, Marya, Müller, Werner, Horvath, Tamas L., Brüning, Jens C.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1502296/
https://ncbi.nlm.nih.gov/pubmed/16818888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0600425103
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