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Impaired germ cell development due to compromised cell cycle progression in Skp2-deficient mice

BACKGROUND: The gonads are responsible for the production of germ cells through both mitosis and meiosis. Skp2 is the receptor subunit of an SCF-type ubiquitin ligase and is a major regulator of the progression of cells into S phase of the cell cycle, which it promotes by mediating the ubiquitin-dep...

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Detalhes bibliográficos
Main Authors: Fotovati, Abbas, Nakayama, Keiko, Nakayama, Keiichi I
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1502135/
https://ncbi.nlm.nih.gov/pubmed/16759351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1747-1028-1-4
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