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Methylation of a CpG Island within the Uroplakin Ib Promoter: A Possible Mechanism for Loss of Uroplakin Ib Expression in Bladder Carcinoma

Uroplakin Ib is a structural protein on the surface of urothelial cells. Expression of uroplakin Ib mRNA is reduced or absent in many transitional cell carcinomas (TCCs) but molecular mechanisms underlying loss of expression remain to be determined. Analysis of the uroplakin Ib promoter identified a...

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Detalhes bibliográficos
Main Authors: Varga, Andrea E, Leonardos, Lefta, Jackson, Paul, Marreiros, Alexandra, Cowled, Prue A
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press Inc. 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1502093/
https://ncbi.nlm.nih.gov/pubmed/15140401
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