Sulf-2, a Proangiogenic Heparan Sulfate Endosulfatase, Is Upregulated in Breast Cancer

Sulf-2 is an endosulfatase with activity against glucosamine-6-sulfate modifications within subregions of intact heparin. The enzyme has the potential to modify the sulfation status of extracellular heparan sulfate proteoglycan (HSPG) glycosaminoglycan chains and thereby to regulate interactions wit...

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Bibliographic Details
Main Authors: Morimoto-Tomita, Megumi, Uchimura, Kenji, Bistrup, Annette, Lum, David H., Egeblad, Mikala, Boudreau, Nancy, Werb, Zena, Rosen, Steven D.
Format: Artigo
Language:Inglês
Published: Neoplasia Press, Inc. 2005
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1502017/
https://ncbi.nlm.nih.gov/pubmed/16331886
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