Sulf-2, a heparan sulfate endosulfatase, promotes human lung carcinogenesis

Heparan sulfate proteoglycans (HSPGs) bind to multiple growth factors/morphogens and regulate their signaling. 6-O-sulfation (6S) of glucosamine within HS-chains is critical for many of these ligand interactions. Sulf-1 and Sulf-2, which are extracellular neutral-pH sulfatases, provide a novel post-...

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Detalhes bibliográficos
Main Authors: Lemjabbar-Alaoui, Hassan, van Zante, Annemieke, Singer, Mark S., Xue, Qing, Wang, Yang-Qing, Tsay, Durwin, He, Biao, Jablons, David M., Rosen, Steven D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2818095/
https://ncbi.nlm.nih.gov/pubmed/19855436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2009.365
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