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Sulf-2, a heparan sulfate endosulfatase, promotes human lung carcinogenesis
Heparan sulfate proteoglycans (HSPGs) bind to multiple growth factors/morphogens and regulate their signaling. 6-O-sulfation (6S) of glucosamine within HS-chains is critical for many of these ligand interactions. Sulf-1 and Sulf-2, which are extracellular neutral-pH sulfatases, provide a novel post-...
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| Hoofdauteurs: | , , , , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2009
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2818095/ https://ncbi.nlm.nih.gov/pubmed/19855436 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2009.365 |
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