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Sulf-2, a Proangiogenic Heparan Sulfate Endosulfatase, Is Upregulated in Breast Cancer

Sulf-2 is an endosulfatase with activity against glucosamine-6-sulfate modifications within subregions of intact heparin. The enzyme has the potential to modify the sulfation status of extracellular heparan sulfate proteoglycan (HSPG) glycosaminoglycan chains and thereby to regulate interactions wit...

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Main Authors: Morimoto-Tomita, Megumi, Uchimura, Kenji, Bistrup, Annette, Lum, David H., Egeblad, Mikala, Boudreau, Nancy, Werb, Zena, Rosen, Steven D.
Formato: Artigo
Idioma:Inglês
Publicado: Neoplasia Press, Inc. 2005
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1502017/
https://ncbi.nlm.nih.gov/pubmed/16331886
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