Hypoxia-Inducible Factor-1α and the Glycolytic Phenotype in Tumors

Metastatic tumors generally exhibit aerobic glycolysis (the Warburg effect). The advent of [(18)F]fluorodeoxyglucose positron emission tomography imaging, coupled with recent findings linking hypoxia-inducible factor (HIF-1α) overexpression to aggressive cancers, has rekindled an interest in this as...

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Autori principali: Robey, Ian F, Lien, Anthony D, Welsh, Sarah J, Baggett, Brenda K, Gillies, Robert J
Natura: Artigo
Lingua:Inglês
Pubblicazione: Neoplasia Press Inc. 2005
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1501147/
https://ncbi.nlm.nih.gov/pubmed/15967109
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