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Contribution of the CK2 Catalytic Isoforms α and α’ to the Glycolytic Phenotype of Tumor Cells

CK2 is a Ser/Thr protein kinase overexpressed in many cancers. It is usually present in cells as a tetrameric enzyme, composed of two catalytic (α or α’) and two regulatory (β) subunits, but it is active also in its monomeric form, and the specific role of the different isoforms is largely unknown....

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Zonta, Francesca, Borgo, Christian, Quezada Meza, Camila Paz, Masgras, Ionica, Rasola, Andrea, Salvi, Mauro, Pinna, Lorenzo A., Ruzzene, Maria
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7831337/
https://ncbi.nlm.nih.gov/pubmed/33477590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10010181
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