Contribution of the CK2 Catalytic Isoforms α and α’ to the Glycolytic Phenotype of Tumor Cells

CK2 is a Ser/Thr protein kinase overexpressed in many cancers. It is usually present in cells as a tetrameric enzyme, composed of two catalytic (α or α’) and two regulatory (β) subunits, but it is active also in its monomeric form, and the specific role of the different isoforms is largely unknown....

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Udgivet i:Cells
Main Authors: Zonta, Francesca, Borgo, Christian, Quezada Meza, Camila Paz, Masgras, Ionica, Rasola, Andrea, Salvi, Mauro, Pinna, Lorenzo A., Ruzzene, Maria
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7831337/
https://ncbi.nlm.nih.gov/pubmed/33477590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10010181
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